Introduction: Occupational pulmonary diseases are more widespread and more disabling than any other group of occupational disease. The lung with its extensive surface area, high blood flow and thin alveolar epithelium is an important site of contact with substance in environment. The inhalation of dust over periods of time leads to proliferation and fibrotic changes in lungs. The workers working in industries suffer from various types of air way diseases like pneumoconiosis, farmer’s lung, chronic bronchitis, pulmonary fibrosis and asthma. So, the present study was undertaken to study the effects of wood dust on respiratory functions of exposed workers Materials and Methods: This is a cross-sectional study was conducted in the Department of Physiology, Shadan Medical College diagnosed with COPD using Spirometry was recruited for the study. Details of the subjects collected at one point of time in the study period. Construction Male workers aged 40-80 years were included. Results The study found significant differences in pulmonary function between the exposed group and the control group. The PEFR, FEV1/FVC ratio, and MVV values were markedly reduced in the exposed group, with mean PEFR values of 350.5 ± 40.3 L/min compared to 420.2 ± 35.6 L/min in the control group (p < 0.001). Similarly, the FEV1/FVC ratio was lower in exposed workers (72.3 ± 6.4%) versus the control group (80.5 ± 5.8%, p < 0.001). MVV was also significantly reduced (85.6 ± 12.1 L/min vs. 102.4 ± 10.8 L/min, p < 0.001). Conclusion This study underscores the adverse effects of wood dust exposure on respiratory health. Regular health surveillance and implementation of protective measures, such as personal protective equipment and adequate ventilation, are recommended to safeguard the respiratory health of wood factory workers