Background: Corneal ulcer is a potentially sight threatening ocular condition and the leading cause of monocular blindness in developing countries. Infectious keratitis can be caused by various pathogens i.e, bacteria, fungi, virus and parasites. Ocular trauma is a far more common predisposing factor of infectious keratitis in developing countries, whereas pre-existing ocular disease and contact lens are common risk factors in developed countries. Hence, an understanding of the aetiologic agents, epidemiologic features and risk factors that occur in specific region are important in rapid recognition, timely institution of therapy, optimal management and prevention of disease entity. Materials and methods: All patients with suspected infectious central corneal ulceration presenting to the ocular microbiology and cornea service. Sociodemographic data and information pertaining to risk factors were recorded, all patients were examined, and corneal cultures and scrapings were performed. Result: A total of 78 patients identified with bacterial corneal ulcer of which 58.97% were males, 37.17% were farmers. Trauma was seen as major predisposing factor in 75.64% cases. The major etiological agent was found in our study was Staphylococcus aureus (60.25%) followed by Pseudomonas in 16.66% and mixed infection in 7.69%. Conclusion: Bacteria are the most common cause of infectious keratitis in this patient population, with coagulase-negative Staphylococcus and Pseudomonas as the most common isolates. The prevalence of culture-positive fungal keratitis is significantly lower than that of bacterial keratitis. Contact lens wear is the most common risk factor associated with infectious keratitis.