Introduction: Unstable proximal humeral fractures are commonly encountered in orthopedic trauma, particularly in elderly patients with osteoporotic bones. Surgical fixation using a proximal humeral locking plate (PHLP) has gained popularity due to its biomechanical stability and ability to promote early mobilization. This study aims to evaluate the effectiveness, functional outcomes, and complication rates associated with PHLP fixation in unstable proximal humeral fractures. Materials and Methods: This prospective cohort study was conducted over a period of 1 year in the Department of Orthopedics. A prospective cohort of 60 patients underwent PHLP fixation, with clinical and radiological follow-up for one year. Patients underwent PHLP fixation under general anesthesia or regional block. A deltopectoral approach was used for exposure. Fracture fragments were reduced and temporarily fixed with K-wires before definitive fixation with PHLP. Postoperative protocol included early passive mobilization, followed by active range-of-motion exercises Results: A total of 60 patients (mean age: 63.4 years) were included in the study. The mean follow-up period was 12 months. The union rate was 93.3%, with an average healing time of 14 weeks. Functional outcomes were assessed using the Constant-Murley Score, with an average score of 78.5 at final follow-up. The most common fracture type in this dataset is the 3-part fracture (25 cases). The right side is more frequently injured (40 cases) compared to the left side (20 cases). The Constant-Murley Score of 78.5 suggests a favorable functional outcome, though not perfect. The range of motion values indicate good recovery in abduction and flexion, but external rotation may still be somewhat limited (normal external rotation is typically around 60-90°). Conclusion: The proximal humeral locking plate is an effective surgical solution for unstable proximal humeral fractures, demonstrating high union rates and satisfactory functional outcomes. Although complications such as screw perforation and avascular necrosis remain challenges, PHLP remains a viable option for improving patient recovery. Further studies with larger sample sizes and longer follow-up periods are needed to refine surgical techniques and optimize patient selection criteria.